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Laurent Nguyen Selected Research

tusamitamab ravtansine

1/2022Integrated multiple analytes and semi-mechanistic population pharmacokinetic model of tusamitamab ravtansine, a DM4 anti-CEACAM5 antibody-drug conjugate.
1/2022Covariate analysis of tusamitamab ravtansine, a DM4 anti-CEACAM5 antibody-drug conjugate, based on first-in-human study.

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Laurent Nguyen Research Topics

Disease

11Neoplasms (Cancer)
01/2022 - 03/2005
3Microcephaly
01/2023 - 12/2015
3Neurodevelopmental Disorders
01/2023 - 01/2022
3Multiple Myeloma
01/2022 - 11/2020
3Breast Neoplasms (Breast Cancer)
10/2016 - 01/2007
3Neurodegenerative Diseases (Neurodegenerative Disease)
06/2014 - 04/2010
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2022 - 03/2008
2Nervous System Diseases (Neurological Disorders)
01/2021 - 01/2010
2Chronic Obstructive Pulmonary Disease (COPD)
01/2021 - 07/2018
2Infections
01/2019 - 01/2018
2Neutropenia
01/2018 - 05/2006
2Neuroblastoma
01/2017 - 03/2005
2Neoplasm Metastasis (Metastasis)
10/2016 - 10/2002
2Lymphoma (Lymphomas)
12/2015 - 03/2005
2Transitional Cell Carcinoma
03/2014 - 03/2008
1Brain Diseases (Brain Disorder)
11/2022
1Rubinstein-Taybi Syndrome (Syndrome, Rubinstein-Taybi)
11/2022
1Binge Drinking
01/2022
1Colitis
01/2022
1Malformations of Cortical Development
01/2022
1Starvation
01/2021
1Hearing Loss (Hearing Impairment)
01/2019
1Yellow Fever
01/2018
1Urinary Bladder Neoplasms (Bladder Cancer)
01/2018
1Seizures (Absence Seizure)
01/2017
1Syndactyly (Polysyndactyly)
11/2016
1Cleft Palate (Palate, Cleft)
11/2016
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2015
1Poisoning
12/2015
1Sickle Cell Anemia (Hemoglobin S Disease)
04/2015
1Learning Disabilities (Learning Disability)
01/2014
1Rhabdomyosarcoma
10/2012
1Iron Overload
04/2012
1Body Weight (Weight, Body)
04/2012
1Ganglion Cysts (Ganglion)
09/2010
1Huntington Disease (Huntington's Disease)
08/2010
1Thalassemia
06/2010
1Deafness (Deaf Mutism)
02/2008
1Carcinoma (Carcinomatosis)
06/2007
1Disease Progression
06/2007
1Leukopenia
01/2007
1Constipation
05/2006

Drug/Important Bio-Agent (IBA)

9Proteins (Proteins, Gene)FDA Link
11/2022 - 10/2002
4vinflunineIBA
01/2018 - 05/2006
4Vinorelbine (Navelbine)FDA LinkGeneric
10/2012 - 10/2002
3isatuximabIBA
01/2022 - 11/2020
3Busulfan (Busulfex)FDA Link
04/2015 - 06/2010
2tusamitamab ravtansineIBA
01/2022 - 01/2022
2PlatinumIBA
01/2018 - 03/2008
2TubulinIBA
01/2018 - 03/2014
2EnzymesIBA
10/2016 - 04/2012
2Biomarkers (Surrogate Marker)IBA
12/2015 - 10/2002
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2003 - 08/2002
1Insulin (Novolin)FDA Link
01/2023
1TransferasesIBA
11/2022
1Lysine (L-Lysine)FDA Link
11/2022
1Histones (Histone)IBA
11/2022
1Ligases (Synthetase)IBA
01/2022
1AlbuminsIBA
01/2022
1pomalidomideIBA
01/2022
1Immunoconjugates (Immunoconjugate)IBA
01/2022
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2022
1Blood Alcohol ContentIBA
01/2022
1CytokinesIBA
01/2022
1Monoclonal AntibodiesIBA
01/2021
1Glucose (Dextrose)FDA LinkGeneric
01/2021
1neonatal Fc receptorIBA
11/2020
1Myeloma ProteinsIBA
11/2020
1Immunoglobulin G (IgG)IBA
11/2020
1Antiviral Agents (Antivirals)IBA
01/2019
1Phosphotransferases (Kinase)IBA
10/2018
1GoldIBA
07/2018
1Bronchodilator Agents (Bronchodilators)IBA
07/2018
1VaccinesIBA
01/2018
1Connexin 43 (Connexin43)IBA
01/2017
1Pentylenetetrazole (Metrazol)IBA
01/2017
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
11/2016
1Transfer RNA (tRNA)IBA
10/2016
1Codon (Codons)IBA
12/2015
1Type II DNA Topoisomerases (Topoisomerase II)IBA
12/2015
1PolyaminesIBA
12/2015
1SpermineIBA
12/2015
1F14512IBA
12/2015
1Topoisomerase II InhibitorsIBA
12/2015
1Endocrine DisruptorsIBA
01/2014
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
10/2012
1DNA (Deoxyribonucleic Acid)IBA
09/2010
1Transcription Factors (Transcription Factor)IBA
09/2010
1CLOCK ProteinsIBA
03/2009
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
01/2007
1Docetaxel (Taxotere)FDA Link
01/2007

Therapy/Procedure

6Therapeutics
01/2021 - 08/2002
2Hematopoietic Stem Cell Transplantation
04/2012 - 06/2010
2Drug Therapy (Chemotherapy)
06/2007 - 01/2007
1Immunotherapy
09/2022
1Secondary Prevention
01/2021
1Injections
12/2015
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
04/2015
1Transplantation
04/2015
1Intravenous Administration
06/2007